Entering Grade Four
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SCIENCE FICTION & FANTASY
Endling series by Katherine Applegate
Book 1: The Last
After her pack is hunted down, Byx believes herself to be the last of a species of mythical dogs--the Endling-- and sets out on a quest to find a safe home.
Fantastic Beasts and Where to Find Them by J.K. Rowling
​The ultimate guide to creatures mysterious and marvelous. 
Frank Einstein series by Jon Sceiszka
Book 1: Frank Einstein and the Antimatter Motor
Kid-genius scientist and inventor Frank accidentally creates smart aleck robots Klink and Klank.  Their plans to win the Midville Science Prize are about to be foiled by Frank's archenemy and possible evil genius, T. Edison.
Fuzzy Mud by Louis Sachar
(also by this author: Wayside School series and Holes)
Tamaya (fifth grade) and Marshall (seventh) take a shortcut through the woods to evade bully Chad. After slinging a handful of mud, Tamaya develops a mysterious rash — which is nothing compared to what happens to Chad. Interspersed are excerpts of testimony from “secret Senate hearings” about a microscopic manmade organism that escaped a laboratory. 
Hiddenseek by Nate Cernosek
Holly and Hector Thorn thought they were playing a simple game of Hide and Seek, until they find themself in a nightmare world being pursued by a shape changing witch whose touch turns children to stone.
Hilo series by Judd Winick
Book 1: The Boy Who Crashed to Earth
When a boy falls from the sky, friends must try to help him figure out who he is, and then help him save the world. (graphic novel)
Ikenga by Nnedi Okorafor
How can a twelve-year-old avenge the murder of his father, the town's respected police chief? Ikenga seems to have an answer when during a mysterious nighttime meeting he is given a magical object and superpowers, that he must use for good. But controlling and using these new-found powers is not such an easy task.
Root Magic by Eden Royce
It's 1963 and 11 year old twins Jez and Jay are about to begin their first year in an integrated school in their South Carolina town. Their uncle Doc is just starting to train them in their family's tradition of African American folk magic. Jez's magical skills are coming just in time to combat both natural and supernatural evils that are about to strike the community.
Sal & Gabi series by Carlos Hernandez
Book 1: Sal & Gabi Break the Universe
Sal has learned to reach into time and space to retrieve things--and people--from other universes. When Sal uses this skill to put a raw chicken in a locker, he comes to Gabi's attention and together they use this trick in various schemes until they learn this constant rearrangement of matter may be threatening the whole universe.
The Unicorn Rescue Society series by Adam Gidwitz
Book 1: The Creature of the Pines
When Elliot starts at a new school, he comes to realize he is now part of a secret group of adventurers responsible for protecting and defending mysterious (and wonderful) creatures.
Wings of Fire series by Tui T. Sutherland
Book 1: The Dragonet Prophecy
Clay must join the other four dragonets to save his world, and he reluctantly takes on the responsibility.
The Witch Boy series by Molly Knox Ostertag
Book 1: The Witch Boy
In Aster's world, boys are shapeshifters and girls are witches. and those who cross the lines are exiled. Problem is, he hasn't shifted yet, he's fascinated by witchery, and he may be able to use it to save the other boys from a mysterious danger. (graphic novel)
The World Between Blinks by Ryan Graudin and Amie Kaufman
Cousins Jake and Marisol follow a treasure map left behind by their grandmother and enter a magical place where lost people and things end up, like Amelia Earhart and Atlantis.  Much as Jake and Marisol are enjoying solving real mysteries from history in the World Between Blinks, they must find a way back home or risk being lost themselves.